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Anaphylactic shock |
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Symptoms of Anaphylaxis or Anaphylactic shock can include respiratory distress, hypotension (low blood pressure), fainting, unconsciousness, urticaria (hives), angioedema (swelling of the face, neck and throat), vomiting and itching. The symptoms are related to the action of immunoglobulin E (IgE) and other anaphylatoxins, which act to release histamine and other mediator substances from mast cells (degranulation). Histamine induces, beside other effects, vasodilation and bronchospasm (constriction of the airways).
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